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Additional resources for ASME Bio Process Equipment (BPE) 2005
The target ratio may not be achievable for weir-type valves clamped to tees and certain sizes of close welded Point-of-Use valves, as shown in Fig. SD-4(a) and (d). For the header and valve size combinations where the target value cannot be met using these configurations, a specific isolation valve design, as shown in Fig. SD4(b) and (c), may be required to achieve the target ratio. 2 Hygienic support systems shall maintain the required pitch and alignment under all operating conditions taking into account thermal cycling, contractions, distortion, settling, etc.
B) Hubs shall have sloped surfaces to prevent holdup of liquids (see Fig. SD-22). (c) Impellers should incorporate drain holes and sloped surfaces to ensure drainage. (d) Flat, horizontal surfaces should be eliminated. (e) Impellers should, if possible, be welded to the shaft. 6 Steady Bearings (a) The use of steady bearings should be avoided. However, if steady bearings are used, then they shall not interfere with the free drainage of the vessel. (b) Pedestal support members shall be constructed from solid bar stock and ensure free drainage of vessel.
Ft (10 mm/m) to a common drain point. (g) All internal surfaces should be sloped or pitched for drainability. 4). All vessels should be checked for drainability during fabrication. 2 Vessel Openings (a) Nozzles that are designed to be cleaned by a spray device should have the smallest L/D ratio possible. For 23 Copyright ASME International Provided by IHS under license with ASME No reproduction or networking permitted without license from IHS --``````,,`,`,,`,,,`,,,,,,`,,,-`-`,,`,,`,`,,`--- Licensee=spirax sarco ltd/5945840001 Not for Resale, 05/24/2006 01:53:20 MDT (05) (05) ASME BPE-2005 BIOPROCESSING EQUIPMENT Same distance Knuckle radius Dome (crown) radius Tangent line GENERAL NOTES: (a) Potential problems with CIP and SIP with capped connections (b) Dead space: stagnant areas (a) Not Recommended Minimum 1 in.